Organic chemistry

unnatural peptide libraries

light-enabled drug delivery

Education

• Postdoctoral Research, Harvard University, 2002-2006
• Ph.D., University of Michigan, 2002
• B.S., Wheaton College, 1997

Research Interests

• Protein-protein interaction inhibitors
• Drug delivery with light
• Fluorescent sensors

Select Publications

H.E.O. Franco, B.T. Chaloux, M.C.T. Hartman Spontaneous, co-translational peptide macrocyclization using p-cyanoacetylene-phenylalanine, Chem. Commun. 2022, 58, 6737-6740

B. Shakya, O.G. Joyner, M.C.T. Hartman. Hyperaccurate Ribosomes for Improved Genetic Code Reprogramming. ACS Synth. Biol. 2022, 11, 2193-2201 

Hacker, D.E.; Abrigo, N.A.; Hoinka, J.; Richardson, S.L.; Przytycka, T.M.; Hartman, M.C.T. Direct, competitive comparison of linear, monocyclic, and bicyclic libraries using mRNA display. ACS Comb. Sci. 2020. 22, 306–310.

E.S. Iqbal, S.L. Richardson, N. Abrigo, K.K. Dods, H.E.O.Franco, H.S. Gerrish, H. Kotapatic, I.M. Morgan, D.S. Masterson, M.C.T. Hartman. A new strategy for the in vitro selection of stapled peptide inhibitors by mRNA display. Chem. Commun. 2019. 55, 8959-8962.

K. Mitra, C.E. Lyons, M.C.T. Hartman*. A Novel Platinum(II) Complex of Heptamethine Cyanine for Photo‐Enhanced Cytotoxicity and Cellular Imaging in Near‐IR Light. Angew. Chem. Int. Ed. 2018, 57, 10263-10267.

Awards

• Outstanding Undergraduate Research Mentor Award, 2012