Education

• Postdoctoral Research, University of Vermont
• Ph.D., Nanjing University

Select Publications

Mangrum, J. B., Zgani, I., Tsotsoros, S. D., Qu Y., Farrell, N. P., “Zinc Finger Peptide Cleavage By a Dinuclear Platinum Compound”, Chem. Commun., 2013, DOI: 10.1039/C3CC44219E

de Paula, Q. A., Tsotsoros, S. D., Bayse, C., Qu Y., Farrell, N. P., “Reactivity of the Platinum-nucleobases in a PtN₄ Chemophore toward Biomolecules”, Special Volume on Metals in Medicine in Inorganic Chimica Acta. 393. 222-229(2012).

Qu, Y., Moniodis, J. J., Harris, A. L., Yang, X., Hegmans, A., Povirk, L. F., Berners-Price, S. J., Farrell, N. P., “Non-Covalent Polynuclear Platinum Compounds as Polyamine Analogs”, Royal Society of Chemistry, Woster, P.M. Ed. 2012  ISBN: 978-1-84973-309-0  DOI:10.1039/9781849733090-00191

Zhou, Q., Qu, Y., Mangrum, J. B., Wang, X., “DNA Alkylation with N-Methylquinolinium Quinone Methide to N2-dG Adducts Resulting in Extensive Stops in Primer Extension with DNA Polymerases and Subsequent Suppression of GFP Expression in A549 Cells”, Chem. Res. Toxicol. 24: 402–411 (2011).

Qu, Y., Tran, M.-C., Farrell, N., “Structural consequences of a 3′ -> 3′ DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex”, JBIC, Journal of Biological Inorganic Chemistry  (2009),  14(6),  969-977.